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Small methods: review of inorganic nano bioelectronic materials for biological interface, regulation and sensing

wallpapers News 2020-07-30
In the past few years

electronic devices of micron submicron scale have shown important applications in the field of Bioelectronics. For example the size of Utah electrode Michigan electrode array for nerve signal sensing is getting smaller smaller the accuracy is improving the damage to organisms is also getting smaller smaller. The electronic devices integrated with sensing control energy supply control units constitute a new closed-loop system which is also the research frontier hot spot in the field of Bioelectronics. The integration of these devices on large scale can show fruitful system applications such as bionic h with sensing feedback function closed-loop optogenetic device with adjustable rat bladder function etc. These new developments provide ideas for the development of nano bioelectronics in the future. It can be predicted that more integrated closed-loop systems will make important progress in biomedical other fields.

nanomaterials devices have many unique advantages in biological research. When the size of the material is small to nano scale it will show many unique optical electrical magnetic properties. Nano electronic devices can detect the coupling between electricity physiology from macro tissue / organ to single cell / organelle. It not only provides an effective way for the use of nanomaterials in physiological signal transduction but also opens the door for the use of nanodevices.

recently Associate Professor Tian Bozhi of the University of Chicago summarized the latest research progress literature reports published "biological interfaces modulation And sensing with inorganic nano bioelectronic materials (DOI: 10.1002/smtd. 201900868) the first author of which is Erik Schaumann a doctoral cidate from the University of Chicago. The paper

discussed summarized the formation regulation sensing of biological interface. In this paper the main characteristics of inorganic nano bioelectronic devices organic nano bioelectronics devices are discussed. The inorganic nano bioelectronics devices in this paper are mainly composed of semiconductors metals the organic nano bioelectronics devices mainly refer to the devices composed of carbon based biological based nano materials. In this paper the author introduces: the preparation of inorganic nanomaterials array has been able to achieve the precise control of structure function but the preparation process is complex the price is high the accumulation effect other side effects may occur in the organism due to the non degradation; the organic nanomaterials have good biocompatibility can be combined with other materials after appropriate modification to build bioelectronic devices It can reduce the mechanical mismatch between cytoskeleton bioelectronic devices so as to avoid the biocompatibility between cytoskeleton bioelectronic devices. It is also mentioned that compared with the reported inorganic nanomaterials the types of organic nanomaterials used in bioelectronic devices are limited the degradation behavior of the materials will also affect the long-term stability of the devices.

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